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Filtered Search Results
Cambridge Isotope Laboratories 2 mM Sucrose 0 25 mM DSS 0 25 mM NaN3 in 90% H2O/10% D2O (v/v) ( 535PP tube) 1 5mm tube
2 mM Sucrose 0 25 mM DSS 0 25 mM NaN3 in 90% H2O/10% D2O (v/v) ( 535PP tube) 1 5mm tube
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Medchemexpress LLC CMP-Sialic acid sodium salt | 1007117-62-5 | 90.8% | 636.43 | 10 MG
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CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. It provides a substrate for Golgi sialyltransferases and is an important sugar nucleotide for the biosynthesis of sialic acid and its conjugates.
- Allosteric inhibitor of UDP-GlcNAc 2-epimerase.
- Provides a substrate for Golgi sialyltransferases.
- Important sugar nucleotide for biosynthesis of sialic acid and its conjugates.
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Medchemexpress LLC 1-(2-(diethylamino)ethyl)-3-(2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl)thiourea | 688342-78-1 | 99.7% | 428.64 | C23H36N6S | 1MG
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D-I03 is a small-molecule selective RAD52 inhibitor used as a research reagent to study RAD52-dependent single-strand annealing and D-loop formation. It shows cellular activity against BRCA1- and BRCA2-deficient cells.
- Selective RAD52 inhibitor with Kd 25.8 μM.
- Inhibits RAD52-dependent single-strand annealing and D-loop formation.
- Cellular activity: suppresses growth of BRCA1- and BRCA2-deficient cells.
- Reported IC50 values: 5 μM (SSA) and 8 μM (D-loop).
- Purity 99.7%.
- Molecular weight 428.64 g/mol; formula C23H36N6S.
- Physical state solid; color off-white to light yellow.
- Solubility in DMSO 50 mg/mL.
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Medchemexpress LLC α-Lactose | 14641-93-1 | 1 ML
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α-Lactose is the major sugar found in milk, existing in two anomeric forms, α and β. The α form typically crystallizes as a monohydrate. As an essential sugar abundant in human and animal milk, it serves as a basic nutrient and a primary substrate for fermentative processes in dairy products like yogurt and kefir. This product is provided with a purity of 98.0% and has a molecular weight of 342.30.
- Major sugar found in milk
- Essential nutrient
- Primary substrate for fermentative processes in dairy products
- Exists in two anomeric forms (α and β)
- α form typically crystallizes as a monohydrate
- Purity: 98.0%
- Molecular weight: 342.30
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Medchemexpress LLC D-Allose | 2595-97-3 | 99.9% | 1 ML
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D-Allose exhibits antitumor activity against various cancer cells. It scavenges reactive oxygen species (ROS) and reduces oxidative stress damage. This compound also shows anti-inflammatory and neuroprotective effects by inhibiting the TLR4/PI3K/AKT signaling pathway. Additionally, D-Allose demonstrates antihypertensive, cryoprotective, and anti-osteoporotic activities.
- Antitumor activity against various cancer cells.
- Scavenges reactive oxygen species (ROS) and reduces oxidative stress damage.
- Anti-inflammatory and neuroprotective effects.
- Antihypertensive, cryoprotective, and anti-osteoporotic activities.
- Inhibits OVCAR-3 cancer cell proliferation and induces apoptosis.
- Upregulates cell cycle inhibitors p21 and p27, arresting cell cycle at G2/M phase.
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Medchemexpress LLC Trehalose 6,6'-dimycolate | 61512-20-7 | MFCD18643296 | 97.0% | 2053.4 g/mol | C130H250O15 | 5 MG
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Trehalose 6,6′-dimycolate (cord factor) is a mycobacterial cell-wall glycolipid used as a research reagent to simulate Mycobacterium tuberculosis-induced inflammation and granuloma formation. It is supplied as a powder for laboratory use and has defined storage and handling recommendations to preserve activity.
- Used to model mycobacterial-induced inflammation and granuloma formation.
- Cell-wall glycolipid (cord factor) relevant to tuberculosis research.
- Purity 97.0%.
- Available in small research pack sizes suitable for in vitro studies.
- Powder form with recommended cold storage to maintain stability.
- Applicable for innate immunity and adjuvant mechanism studies.
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Medchemexpress LLC D-BIOTINOL 10MM 1ML
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5000204755 D-BIOTINOL 10MM 1ML
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Crescent Chemical Co Inc D(+)-TREHALOSE DIHYDRATE 250MG
D(+)-Trehalose dihydrate Food related compounds (WS) CAS 6138-23-4 Molecular Weight - 378.327 Storage - RT Catalog Num - DRE-C17607500 chemical
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Medchemexpress LLC Galactose 1-phosphate | 2255-14-3 | 99.98% | 260.14 | 10 MG
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Galactose 1-phosphate is an intermediate in galactose metabolism and nucleotide sugars.
- At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity.
- The salt form usually boasts enhanced water solubility and stability.
- For research use only.
- We do not sell to patients.
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Chem-Impex International, Inc. 5-Bromo-4-chloro-3-indolyl b-D-glucopyranoside | MFCD00063690 | 5G
5-Bromo-4-chloro-3-indolyl b-D-glucopyranoside, MFCD00063690, 5G
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Medchemexpress LLC D-α-Tocopherylquinone | 7559-04-8 | 5 MG
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D-α-Tocopherylquinone is a quinone isolated from *Phaeodactylum tricornutum* and an oxidation product of α-Tocopherol (vitamin E). It functions as an anticoagulant and antioxidant, actively reducing cellular oxidative damage caused by oxidized lipids. The compound binds to a liver cytosolic protein (molecular mass ~40 kDa) and to glutathione-S-transferase (GST), which aids its transport to metabolism sites or excretion in bile.
- Isolated from *Phaeodactylum tricornutum*
- Oxidation product of α-tocopherol (vitamin E)
- Acts as an anticoagulant
- Acts as an antioxidant
- Reduces cellular oxidative damage from oxidized lipids
- Binds to a liver cytosolic protein
- Binds to glutathione-S-transferase (GST)
- Facilitates transport for metabolism or excretion
- Inhibits GST activity dose-dependently
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Medchemexpress LLC D-64131 | 74588-78-6 | C16H13NO2 | 5 MG
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D-64131 is an orally active tubulin inhibitor with an IC50 of 0.53 μM for tubulin polymerization. It has antimitotic activity and can be used for cancer research. It is antimitotic by binding to β-tubulin, which destabilizes microtubules and arrests mitotic cells in the M-phase. It inhibits the proliferation of tumor cells from 12 of 14 different organs and tissues with mean IC50s of 62 nM. It is also cytotoxic towards MDR/MRP tumor cell lines. In vivo studies have shown that D-64131 significantly inhibits tumor growth in human amelanoic melanoma MEXF 989 tumor xenograft mice models and exhibits oral bioavailability, being well tolerated at efficacious doses.
- Orally active tubulin inhibitor
- Potent antimitotic activity
- Broad-spectrum anti-tumor activity
- Cytotoxic to drug-resistant cell lines
- Well-tolerated in vivo
- Research use only
- High purity
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Medchemexpress LLC [D-Trp34]-Neuropeptide Y | 153549-84-9 | 99.7% | 4311.72 | 5 MG
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[D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist, showing significantly less potency at NPY Y1, Y2, Y4, and y6 receptors. This compound is known to markedly increase food intake in rats.
- Potent and selective NPY Y5 receptor agonist
- Significantly less potent at NPY Y1, Y2, Y4, and y6 receptors
- Increases food intake in rats
- Soluble in water at 100 mg/mL (23.19 mM)
- Appears as a white to off-white solid
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Medchemexpress LLC D-Psicose-d (D-Allulose-d) | 53685-24-8 | 99.9% | 181.16 | 5 MG
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D-Psicose-d is the deuterium labeled D-Psicose. D-psicose is an orally active rare sugar that inhibits p38-MAPK phosphorylation and MCP-1 expression. It also inhibits the AGEs/RAGE/NF-κB pathway. D-psicose protects pancreatic β-islets, improving hyperglycemia and high-fat diet-induced non-alcoholic fatty liver disease.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
- Deuteration affects the pharmacokinetic and metabolic profiles of drugs.
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Medchemexpress LLC Alpha Sarcoglycan Antibody (YA2068) | 10 UL
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The alpha Sarcoglycan Antibody (YA2068) is a Rabbit-derived, non-conjugated IgG monoclonal antibody designed to target alpha Sarcoglycan. Alpha Sarcoglycan is a component of the sarcoglycan complex, which forms a structural link between the F-actin cytoskeleton and the extracellular matrix.
- Applications include WB, IHC-P, and IP
- Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Store at -20°C for 1 year
- Avoid repeated freeze/thaw cycles
- Liquid appearance
- Rabbit host
- Reactivity with human, mouse, and rat samples
- Non-conjugated
- Affinity purified
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